Taxane Compound

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Information
Drug Name
Taxane Compound
Description
Entry(CIViC)
3
CIViC
Disease Mutation EL ET ED CS VO TR Pubmed Links
lung non-small cell carcinoma BIRC5 EXPRESSION BIRC5 NUCLEAR EXPRESSION B Predictive Supports Sensitivity/Response N/A 3 24961465 Detail
breast cancer TUBB3 EXPRESSION TUBB3 EXPRESSION B Predictive Supports Sensitivity/Response N/A 2 23218766 Detail
ovarian cancer BRCA1 UNDEREXPRESSION
( ENST00000357654.9 ) BRCA1 UNDEREXPRESSION
( ENST00000357654.9 ) 		B Predictive Supports Sensitivity/Response Somatic 3 21920589 Detail
Annotation
Description Associated Genes Associated Variants Sensitivity Supported Source Links
Patients with nuclear survivin (BIRC5) expression ... BIRC5 BIRC5 EXPRESSION BIRC5 NUCLEAR EXPRESSION Sensitivity true CIViC Evidence detail
High expression of betaIII-tubulin, as assessed in... TUBB3 TUBB3 EXPRESSION TUBB3 EXPRESSION Sensitivity true CIViC Evidence detail
Absent/low expression of BRCA1 (IHC) was associate... BRCA1 BRCA1 UNDEREXPRESSION
( ENST00000357654.9 ) BRCA1 UNDEREXPRESSION
( ENST00000357654.9 ) 		Sensitivity true CIViC Evidence detail